Synthetic Chemistry 14 – Chirality in Drug Discovery

Clinical ChemistryStereochemistry is the study of chemistry in 3D and involves molecules which have the same molecular formula, but differ in their orientations in space.  Chirality is one form of stereoisomerism involving molecules (enantiomers) in which their mirror images are not superimposable. Therefore, enantiomers have distinct structure and interact with biological systems in different ways. The course will develop awareness for different chirality forms and increase your knowledge of the important role that chirality has in the drug discovery process. Chiral purity and separation techniques will be discussed as well as the determination of the absolute stereochemistry.