Flash Chromatography is a tool that has been in use by chemists to isolate intermediates and final compounds since the early 1900’s. In recent years, the procedure has been simplified by the advances in automated equipment and the improved consistency of silica gel production. This lecture will take you through some of the fundamentals of normal phase flash chromatography, specific techniques that all chemist need to be aware off as well as the step-s in designing a successful gradient.