As a person who works with animals, your job is one of the most important in biomedical research. Veterinarians, researchers, and the animals themselves rely on you to notice changes and help ensure the well-being of the animals in your care. Recognizing clinical or behavioral signs of illness or stress is not only a welfare issue, but a scientific one, as some of these conditions have the potential to disrupt research projects.

Based on the Handbook of Clinical Signs in Rodents and Rabbits, this training will review some of the more common signs you may observe when working with these animals.

This scenario-based module will review a potential genetic contamination within a fictional rodent production facility.  Please work through the information and challenges presented to see who well you would respond if the situation were real.

This course is intended for Charles River Research Models and Services (RMS) animal care, husbandry and veterinary staff.

This course focuses on the processes and procedures utilized to detect, manage, monitor and respond to genetic contaminations in Charles River RMS animal colonies.

Leaks that carry water from uncontrolled and possibly contaminated areas can carry unwanted infections agents into biosecure spaces supporting the breeding and production of research models.  This course provides a brief overview of the steps to be followed by animal husbandry and facilities staff in the event of water penetrates into RMS production areas including barrier rooms, isolator areas, and critical control areas that support production operations.


Welcome to first global biosecurity training topic.  This training will cover Pest Control.

Learning objectives include:

  • Identify important/relevant pests that pose the greatest risk to our colonies
  • Review some basic behavior of those pests, as this is important to as we design pest control practices to protect our facilities and colonies
  • Review the primary control measures we use to safe guard our facilities and colonies against pests

About this course: This module will review the current Charles River Biosecurity Alert System.  The module defines what a biosecurity alert event and why it is important.

Intended Audience:  This training is recommended for all Charles River Research Models and Services (RMS) personnel working in an RMS production or breeding facility.


About this course: This module will review the current Charles River Biosecurity Alert System.  The module defines what a biosecurity alert event and why it is important.

Intended Audience:  This training is recommended for all Charles River Research Models and Services (RMS) personnel working in an RMS production or breeding facility.


Welcome to first global biosecurity training topic.  This training will cover Pest Control.

Learning objectives include:

  • Identify important/relevant pests that pose the greatest risk to our colonies
  • Review some basic behavior of those pests, as this is important to as we design pest control practices to protect our facilities and colonies
  • Review the primary control measures we use to safe guard our facilities and colonies against pests

A successful surgical protocol requires careful monitoring of the entire perioperative process. Failure to properly monitor the animal and to provide adequate care may result in delayed anesthesia recovery and may increase surgery-related issues. Proper perioperative care of laboratory animals is also linked to effective application of the 3Rs principle.

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A basic understanding of mouse behavior is essential to properly care for these animals, to provide an adequate environment and to efficiently and effectively manage GEM colonies. A basic understanding of species-specific behavior will allow you to:

  • Provide mice with an environment to enhance their well-being
  • Recognize abnormal behaviors
  • Minimize the influence of undesired behaviors in experimental results and animal welfare

This short course compiles basic knowledge on normal mouse behavior (mouse ethogram), along with a description of aberrant behaviors that can be observed in the laboratory mouse. It also provides hints on how to avoid or reduce these behaviors.



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